There is no solid data about ASMR, no published research studies — not yet. The term “ASMR” is nonclinical, coined in 2010 by a woman named Jennifer Allen who started an ASMR Facebook group and later became part of a team — along with Richard — that collected and analyzed anecdotal information about the sensation. Richard also notes the work of Bryson Lochte, a Dartmouth College undergrad who has used neuroimaging technology to study ASMR for his senior thesis but has not published his results.

On 12 March 2012, Steven Novella, Director of General Neurology at the Yale School of Medicine, published a post about ASMR on his blog Neurologica. Regarding the question of whether ASMR is a real phenomeonon, Novella said "in this case, I don't think there is a definitive answer, but I am inclined to believe that it is. There are a number of people who seem to have independently experienced and described" it with "fairly specific details. In this way it's similar to migraine headaches – we know they exist as a syndrome primarily because many different people report the same constellation of symptoms and natural history." Novella tentatively posited the possibilities that ASMR might be either a type of pleasurable seizure, or another way to activate the "pleasure response". However, Novella drew attention to the lack of scientific investigation into ASMR, suggesting that functional magnetic resonance imaging (fMRI) and transcranial magnetic stimulation technologies should be used to study the brains of people who experience ASMR in comparison to people who do not, as a way of beginning to seek scientific understanding and explanation of the phenomenon.[39][40]
1. Do you have different reactions depending on who is the source of the sound? For example, I have very distinctive reactions, i.e. if someone from my relatives does the mouth sounds, I get irritated and at times even angry. I even leave the kitchen if I hear my relatives making the sounds while eating. Purely biological, can’t explain it. The sounds are unpleasant for me. But if a random person or someone I barely know from an opposite sex does the mouth sounds, I can get ASMR or pleasurable feelings.
ASMR is usually precipitated by stimuli referred to as 'triggers'.[11] ASMR triggers, which are most commonly auditory and visual, may be encountered through the interpersonal interactions of daily life. Additionally, ASMR is often triggered by exposure to specific audio and video. Such media may be specially made with the specific purpose of triggering ASMR or originally created for other purposes and later discovered to be effective as a trigger of the experience.[4]