For those who don't experience ASMR, it can be difficult to wrap your head around this "tingling" feeling and how something as simple as whispering or clicking could trigger it. But recent research has shown that ASMR is more than just a self-reported feeling—it can be measured physiologically. A 2018 study published in the journal PLOS One found that people who watched ASMR videos had a decreased heart rate in response, which can explain the intense feeling of relaxation many people report. Researchers also recorded higher levels of skin conductance in people experiencing ASMR, indicating arousal or excitement (likely due to the tingles).
Austrian writer Clemens J. Setz suggests that a passage from the novel Mrs. Dalloway authored by Virginia Woolf and published in 1925, describes something distinctly comparable. In the passage from Mrs. Dalloway cited by Setz, a nursemaid speaks to the man who is her patient 'deeply, softly, like a mellow organ, but with a roughness in her voice like a grasshopper's, which rasped his spine deliciously and sent running up into his brain waves of sound'.
Anyway, I have no problem sleeping, ever. I usually have a problem getting to bed, because I fall asleep wherever I’m sitting. My big problem is being intimate. If I’m in the middle of business, and I start thinking about my girlfriend’s body touching parts of the right side of my body, I start getting severe tickles and I’ve tossed her to the side because it’s too much for me. It’s one of those things where you tell yourself not to think about it, but it makes you think about it more. My right knee is the worst part. Anyone comes near that knee, not even touching it – they could just sit next to me, and if their leg touches my knee occasionally – I get tickle fits.
Another article, "Autonomous Sensory Meridian Response (ASMR): a flow-like mental state", by Nick Davis and Emma Barratt, lecturer and post-graduate researcher respectively in the Department of Psychology at Swansea University, was published in PeerJ. This article aimed to 'describe the sensations associated with ASMR, explore the ways in which it is typically induced in capable individuals ... to provide further thoughts on where this sensation may fit into current knowledge on atypical perceptual experiences ... and to explore the extent to which engagement with ASMR may ease symptoms of depression and chronic pain' The paper was based on a study of 245 men, 222 women, and 8 individuals of non-binary gender, aged from 18 to 54 years, all of whom had experienced ASMR, and regularly consumed ASMR media, from which the authors concluded and suggested that 'given the reported benefits of ASMR in improving mood and pain symptoms...ASMR warrants further investigation as a potential therapeutic measure similar to that of meditation and mindfulness.'
In the first peer-reviewed article on ASMR, published in Perspectives in Biology in summer 2013, Nitin Ahuja, who was at the time of publication a medical resident at the University of Virginia, invited conjecture on whether the receipt of simulated medical attention might have some tangible therapeutic value for the recipient, comparing the purported positive outcome of clinical role play ASMR videos with the themes of the novel Love in the Ruins by author and physician Walker Percy, published in 1971.