Emotionally, Kelly and Daniel seem equipped to deal with this backlash (Aoki Hunnicutt remains blissfully unaware of any negativity, and also much else about YouTube fame – at one point during our interview, she asks with concern, “Mummy, I thought we were going to do an interview?”). Yet while they are fine with their fame, it may trouble the young stars to lose it.
The first study to perform actual brain imaging (fMRI) on subjects currently experiencing ASMR tingles (as opposed to individuals who were merely able to experience the phenomenon) was published in BioImpacts in September 2018. Subjects viewed several ASMR videos with a screen and headphones while inside the MRI scanner. The study found a significant difference in brain activation between time periods when the subject reported tingling (communicated by pressing a button), as compared to time periods when they were watching a video but not reporting tingling (communicated by pressing a different button, to control for brain activation effects caused by merely pressing a button). They concluded that "the brain regions found most active during the tingling sensations were the nucleus accumbens, mPFC, insula and secondary somatosensory cortex", and suggested that these were similar to "activation of brain regions previously observed during experiences like social bonding and musical frisson".
ASMR is usually precipitated by stimuli referred to as 'triggers'. ASMR triggers, which are most commonly auditory and visual, may be encountered through the interpersonal interactions of daily life. Additionally, ASMR is often triggered by exposure to specific audio and video. Such media may be specially made with the specific purpose of triggering ASMR or originally created for other purposes and later discovered to be effective as a trigger of the experience.