An article titled "An examination of the default mode network in individuals with autonomous sensory meridian response (ASMR)"[38] by Stephen D. Smith, Beverley Katherine Fredborg, and Jennifer Kornelsen, looked at the default mode network (DMN) in individuals with ASMR. The study, which used functional magnetic resonance imaging (fMRI), concluded that there were significant differences in the DMN of individuals who have ASMR as compared to a control group without ASMR.
I’m not sure how to say this, but I’ll try. I think this experience is a spiritual one. I get the impression that when we appreciate something so simple and quiet this pleases God. It’s our own willingness to accept such “insignificant” events and appreciate the beauty of things which would otherwise be discarded in our noisy and materialistic lives. The appreciation of “small” things, be it sounds, sensations, smells which would otherwise be ignored really pleases our Creator, these sensations are a gift, a “thank you” for appreciating the wonder of nature and creation in all its beauty, especially the seemingly insignifcant moments and events in time ignored and forgotten by mankind…
These reports have precipitated comparison between ASMR and synesthesia – a condition characterised by the excitation of one sensory modality by stimuli that normally exclusively stimulates another, as when the hearing of a specific sound induces the visualization of a distinct color, a type of synesthesia called chromesthesia. Thereby, people with other types of synesthesia report for example 'seeing sounds' in the case of auditory-visual synesthesia, or 'tasting words' in the case of lexical-gustatory synesthesia.[42][43][44][45][46]
Allen verified in a 2016 interview that she purposely selected these terms because they were more objective, comfortable, and clinical than alternative terms for the sensation.[10] Allen explained she selected the word meridian to replace the word orgasm due to its meaning of point or period of greatest prosperity.[clarification needed][citation needed]