In the limited, small studies that have been done investigating ASMR, there do appear to be brain abnormalities in people who experience ASMR, though this is far from confirmed. But some studies did find that people who experience the phenomenon appear to have brains that are wired differently when it comes to the areas that react to sensory perception. Instead of two sensory areas having a clear connection in their brain, a tinglehead’s sensory areas of the brain appear to blend together to some degree. Some neurologists who have studied the phenomena even think ASMR could be related to the bizarre condition of synesthesia, where a person can hear smells or see music.
ASMR is usually precipitated by stimuli referred to as 'triggers'.[11] ASMR triggers, which are most commonly auditory and visual, may be encountered through the interpersonal interactions of daily life. Additionally, ASMR is often triggered by exposure to specific audio and video. Such media may be specially made with the specific purpose of triggering ASMR or originally created for other purposes and later discovered to be effective as a trigger of the experience.[4]