While little scientific research has been conducted into potential neurobiological correlates to the perceptual phenomenon known as 'autonomous sensory meridian response' (ASMR), with a consequent dearth of data with which to either explain or refute its physical nature, there is voluminous anecdotal literature comprising personal commentary and intimate disclosure of subjective experiences distributed across forums, blogs, and YouTube comments by hundreds of thousands of people. Within this literature, in addition to the original consensus that ASMR is euphoric but non-sexual in nature, a further point of continued majority agreement within the community of those who experience it is that they fall into two broad categories of subjects.

ASMR is usually precipitated by stimuli referred to as 'triggers'.[11] ASMR triggers, which are most commonly auditory and visual, may be encountered through the interpersonal interactions of daily life. Additionally, ASMR is often triggered by exposure to specific audio and video. Such media may be specially made with the specific purpose of triggering ASMR or originally created for other purposes and later discovered to be effective as a trigger of the experience.[4]